Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by specific loss of motor neurons in the spinal cord and brain stem. Although ALS has historically been characterized as a motor neuron disease. there is evidence that motor neurons degenerate in a retrograde manner. beginning in the periphery at the neuromuscular junctions (NMJs) and skeletal muscle. https://trendingcustomes.shop/product-category/puzzle-acrylic-plaque/